Get Help Managing a Type of Severe Asthma

See the illustration below to understand what could be behind your severe asthma symptoms.

Do You Have Severe, Poorly Controlled Asthma?

Asthma can be a lifelong disease for millions of people. People with asthma often have similar symptoms. However, these symptoms can vary by patient. Asthma can be mild, moderate, or severe. Your doctor can determine if your asthma is severe. This is based on your symptoms, medical history, and test results.

A small group of people may have severe, poorly controlled asthma despite taking treatment. That means that, even though you take multiple asthma medicines, you may still:

  • Have frequent asthma attacks (exacerbations) which may require an emergency room or hospital visit
  • Lack control over your symptoms
  • Have trouble breathing (poor lung function)
  • Take oral steroid medications for an asthma attack
Find out if Eosinophils could be a factor in your poorly controlled asthma

How do you say eosinophil?

Eosinophil is pronounced:

What Are Eosinophils?

Eosinophils: A cause of inflammation

Asthma results from exposure to certain triggers, causing airway inflammation or swelling. This inflammation is caused by many types of cells and may include a high level of cells called eosinophils. Eosinophils can travel to the lungs and cause your airways to swell and narrow. Lung inflammation can be a cause of severe asthma.

High eosinophil levels may contribute to severe, poorly controlled asthma

Your doctor can measure your eosinophil level with a simple blood test. Your test results may show a high level of eosinophils. In this case, your doctor may recommend additional treatment.

Learn what to do if your asthma is poorly controlled

How Can You Know if Your Asthma is Poorly Controlled?

The first step is to speak with your doctor

When your asthma is difficult to control, it can affect your daily life. It also affects how you breathe, how many asthma attacks you have, and the severity of those attacks. You may have used many different treatments to try to get it under control. If you continue to have asthma symptoms or attacks, ask your doctor about your eosinophil level. Together, you and your doctor can find the right treatment.

Find out more about CINQAIR


Important Safety Information

What is the most important information I should know about CINQAIR?

CINQAIR can cause serious side effects, including:

Serious allergic reactions (anaphylaxis). Serious allergic reactions can happen right after you receive your CINQAIR infusion. These reactions can cause death. Allergic reactions sometimes do not happen right away. Your healthcare provider will watch you during and after you receive your CINQAIR infusion for any signs of a reaction.

Tell your healthcare provider right away if you have any of the following symptoms that may be associated with an allergic reaction:

  • breathing problems
  • paleness
  • flushing
  • skin rash (hives)
  • itching
  • swelling of your face, lips, mouth, or tongue
  • symptoms of low blood pressure (fainting, dizziness, light headedness, confusion, fast heart beat)
  • nausea or abdominal discomfort

What is CINQAIR?

CINQAIR is a prescription medicine used with other asthma medicines for the maintenance treatment of asthma in people aged 18 years of age and older whose asthma is not controlled with the current asthma medicines. When added to other medicines for asthma, CINQAIR helps prevent severe asthma attacks (exacerbations) and can improve your breathing. Medicines such as CINQAIR reduce blood eosinophils. Eosinophils are a type of white blood cell that may contribute to your asthma.

  • CINQAIR is not used to treat other problems caused by eosinophils.
  • CINQAIR is not used to treat sudden breathing problems.

It is not known if CINQAIR is safe and effective in children less than 18 years of age.

Do not receive CINQAIR if you are allergic to reslizumab or any of the ingredients in CINQAIR.

See the Full Prescribing Information for a complete list of ingredients in CINQAIR.

Before receiving CINQAIR, tell your healthcare provider about all of your medical conditions, including if you:

  • are taking oral or inhaled corticosteroid medicines. Do not stop taking your corticosteroid unless your healthcare provider tells you to stop. This may cause other symptoms that were controlled by the corticosteroid medicine to come back.
  • have or have had cancer (malignancy).
  • have a parasitic (helminth) infection.
  • are pregnant or plan to become pregnant. It is not known if CINQAIR will harm your unborn baby. Tell your healthcare provider if you become pregnant during your treatment with CINQAIR.
  • are breastfeeding or plan to breastfeed. It is not known if CINQAIR passes into your breast milk. You and your healthcare provider should decide if you will receive CINQAIR and breastfeed. Talk to your healthcare provider about the best way to feed your baby if you receive CINQAIR.

Do not stop taking your other asthma medicines unless your healthcare provider tells you to.

What are the possible side effects of CINQAIR?

CINQAIR may cause serious side effects, including:
  • See “What is the most important information I should know about CINQAIR?”
  • abnormal growth of cells or tissue in your body that may or may not be cancer (malignancy)
The most common side effects of CINQAIR include throat pain.

These are not all the possible side effects of CINQAIR.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see the Full Prescribing Information.
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