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Poorly controlled, severe eosinophilic asthma is a type of asthma with symptoms that are difficult to control – even if you’re taking multiple medications.

Here are some important signs:

• Even if you’re taking multiple asthma medications, you still have symptoms every day.
• Blood tests show that you have high levels of white blood cells called eosinophils.
• You sometimes have to take oral steroids for asthma attacks.
• Symptoms wake you up at night.
• You’ve been to the emergency room or stayed in the hospital more than twice in a year due to asthma symptoms.

Eosinophils are white blood cells that help fight infection and illness. We all have eosinophils. They’re a normal part of our immune systems

But some people with severe asthma have too many eosinophils. High levels can lead to inflammation of the airways, asthma symptoms, and asthma attacks.

Learn more about how high eosinophils can impact asthma symptoms.

Your doctor can measure your eosinophil levels with a simple blood test.

CINQAIR is a prescription medicine used with other asthma treatments for the maintenance treatment of asthma in people aged 18 years of age and older whose asthma is not controlled with current asthma medicines and who have high levels of eosinophils (a type of white blood cell).

CINQAIR can reduce severe, uncontrolled eosinophilic asthma symptoms and attacks, improve breathing, and improve quality of life.

Learn more about the benefits of CINQAIR.

CINQAIR blocks the growth of eosinophils that lead to airway inflammation and asthma symptoms. That means lower levels of eosinophils and reduced asthma symptoms^*.

Learn more about how CINQAIR works.

*The mechanism of Cinqair action in asthma has not been definitively established.

Do not receive CINQAIR if you are allergic to reslizumab or any of the ingredients in CINQAIR.

Visit Full Prescribing Information for a complete list of the ingredients in CINQAIR.

Before receiving CINQAIR, tell your doctor about all of your medical conditions, including if you:

• are taking oral or inhaled corticosteroid medicines. Do not stop taking your corticosteroid unless your healthcare provider tells you to stop. This may cause other symptoms that were controlled by the corticosteroid medicine to come back.
• have or have had cancer (malignancy).
• have a parasitic (helminth) infection.
• are pregnant or plan to become pregnant. It is not known if CINQAIR will harm your unborn baby. Tell your healthcare provider if you become pregnant during your treatment with CINQAIR.
• are breastfeeding or plan to breastfeed. It is not known if CINQAIR passes into your breast milk. You and your healthcare provider should decide if you will receive CINQAIR and breastfeed. Talk to your healthcare provider about the best way to feed your baby if you receive CINQAIR.

CINQAIR can cause serious side effects, including

• Abnormal growth of cells or tissue in your body that may or may not be cancer (malignancy).
• Serious allergic reactions (anaphylaxis).

  Serious allergic reactions can happen right after you receive your CINQAIR infusion. These reactions can cause death. Allergic reactions sometimes do not happen right away. Your healthcare provider will watch you during and after you receive your CINQAIR infusion for any signs of a reaction.

  Tell your healthcare provider right away if you have any of the following symptoms that may be associated with an allergic reaction:

• breathing problems
• paleness
• flushing
• skin rash (hives)
• itching
• swelling of your face, lips, mouth, or tongue
• symptoms of low blood pressure (fainting, dizziness, light headedness, confusion, fast heart beat)
• nausea or abdominal discomfort

The most common side effects of CINQAIR include throat pain. These are not all the possible side effects of CINQAIR. Call your doctor for medical advice about side effects of CINQAIR. You may report side effects to FDA at 1-800-FDA-1088.

CINQAIR may be right for you if:

• You have asthma symptoms (wheezing, chest tightness, shortness of breath, or cough) two or more days per week even though you are taking multiple asthma medications.
• Asthma has impacted your day-to-day life.
• You’ve had to use a rescue inhaler more than twice in one week.
• Symptoms interfere with your daily activities.
• You’ve had to take oral steroids for one or more asthma attacks over the last 12 months.
• You have needed urgent medical care because of asthma.
• Your peak flow rates are lower than they have been in the past.
• Your lung function (breathing) test results are below normal.
• You have taken a blood test that shows high levels of eosinophils in your blood.
• You are 18 years old or older.

If you are taking multiple asthma medications but still have symptoms, talk to your doctor to see if CINQAIR may be right for you.

Learn more and download a discussion guide to help you start the conversation.

CINQAIR is an IV infusion given by a healthcare provider using a needle placed in your vein. CINQAIR is given once every 4 weeks. It takes about 20 to 50 minutes to receive the full dose of CINQAIR. CINQAIR can be given in your doctor’s office, in an infusion center, or in your home.

CINQAIR is an “add-on” medication: it’s taken along with the medications you are already taking, such as inhalers and oral steroids. If you and your doctor decide that CINQAIR is right for you, keep taking your other asthma medications unless your doctor tells you not to.

Learn More about taking CINQAIR.

If you and your doctor decide that CINQAIR is right for you, do not stop taking your other asthma medications. Keep taking them unless your doctor tells you not to.

How much you pay for CINQAIR depends on the type of health insurance coverage you have. If you have commercial health insurance coverage for CINQAIR, you may pay as little as $0 out-of-pocket for the cost of CINQAIR and its administration (up to $10,000 per year).^*

Visit Savings and Support for more information.

The CINQAIR Cost Support Program helps commercially insured individuals in the United States (including the United States territories) who are prescribed CINQAIR pay for their eligible out-of-pocket costs for the drug and for administration of the drug, including co-pays, co-insurance, and deductibles.

Persons residing in a state that does NOT allow financial assistance for the administration of the drug may ONLY be eligible to receive out-of-pocket cost support for the drug.

The Program does not cover the costs of physician office visits or evaluations, blood work or other testing, or transportation. Eligible individuals must have commercial insurance for CINQAIR. Uninsured and cash-paying patients are NOT eligible for this Program, nor are individuals with commercial insurance coverage that does not provide coverage for CINQAIR.

Talk to your Healthcare Provider or Insurance Provider for complete Terms and Conditions.

When your doctor prescribes CINQAIR, you can enroll in the Teva Support Solutions^® program for personalized support for understanding your treatment, insurance, and financial assistance options.

Visit Savings and Support for more information.

The Teva Patient Services Portal is a website where you can connect with services to help you along your treatment path. On the portal, you can apply for financial assistance, enroll in a copay assistance program, and more. Visit the portal and click on the CINQAIR link for more information.

If you choose to receive CINQAIR at home, Teva Support Solutions^® will arrange to have a specialty pharmacy deliver CINQAIR to your home in time for your treatment appointment.

Visit Savings and Support for more information.

Visit Patient Resources for helpful appointment reminders:

• Easily set up electronic reminder alerts you can receive on your computer or smartphone.
• Download and print a treatment tracker to write down your upcoming appointments.